determination of rifampin and isoniazid resistant mycobacterium tuberculosis in kermanshah (2006-2008)

tuberculosis is one of the most important infectious diseases and a major cause of morbidity and mortality in developing countries. multi drug resistant tuberculosis is a new threat, which can result in a high case fatality rate. this study was conducted to define the incidence of multidrug resistant tuberculosis in kermanshah. ­antibiogram was performed on­­ pcr-confirmed isolates of mycobacterium tuberculosis by using the proportion method. eight cases (57.1%) showed resistance to ­1µg/ml isoniazid­. resistance to rifampicin was identified in 46.2% ­of cases.­ this study showed a high rate of single drug and multidrug resistance. we recommend antibiogram for all cases of tuberculosis.